منابع مشابه
Multidrug resistance: a solvable problem?
The results of chemotherapy of pancreatic cancer have been disappointing thusfar. Pancreatic tumors are primary resistant to available drugs. Why that is, is as hard to define as why normal tissues are resistant. Meaningful studies on drug resistance of pancreatic tumors can only be expected after a highly effective drug has been found. While waiting for this magic bullet to arrive, I shall rev...
متن کاملA Variety with Solvable, but Not Uniformly Solvable, Word Problem
In the literature two notions of the word problem for a variety occur. A variety has a decidable word problem if every finitely presented algebra in the variety has a decidable word problem. It has a uniformly decidable word problem if there is an algorithm which given a finite presentation produces an algorithm for solving the word problem of the algebra so presented. A variety is given with f...
متن کاملMultidrug resistance associated proteins in multidrug resistance
Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer dru...
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Bacterial infections may cause disease and death. Infants and children are often subject to bacterial infections. Antimicrobials kill bacteria protecting the infected patients andreducing the risk of morbidity and mortality caused by bacteria. The antibiotics may lose their antibacterial activity when they become resistant to a bacteria. The resistance to different antibiotics in a bacteria is ...
متن کاملMultidrug resistance in fungi.
One of the major advances serving to define the beginning of the era of modern medicine was the development of penicillin in the early 1940s as the first widely used antibiotic effective against microorganisms (reviewed in reference 111). In what has become an all-too-common trend, antibiotic-resistant isolates emerged soon after the large-scale use of penicillin to treat bacterial infections (...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1999
ISSN: 0923-7534
DOI: 10.1093/annonc/10.suppl_4.s162